Drs Shousha and Boxer reply as follows

Drs. Negoescu and Abraham reply.

Drs. Waljee and Chung reply.

Drs. Moon and Min reply.

Drs. Littlejohn and Guymer reply.

Reply to Drs. Teppema, Berendsen, and Swenson.

TO THE EDITOR: We followed with great interest the recent exchanges between Drs. Teppema and Berendsen (4) on one hand and Dr. Swenson on the other hand regarding the mechanisms of effects of acetazolamide (AZ) in the prevention of Acute Mountain Sickness (AMS) (3). One of the essential questions raised by both parts is the action of AZ on central and peripheral chemosensitivity, respectively. ...